Biol. Pharm. Bull. 29(9) 1970—1972 (2006)
نویسندگان
چکیده
MAXIM. (Aceraceae) (Japanese name, Megusurino-ki) has been used as a folk medicine for the treatment of hepatic disorders and eye disease. The bark has been reported to contain various diarylheptanoid and phenolic compounds possessing several biological properties including hepatoprotective effects. In the course of our studies on the bioactive principles from natural sources, we have evaluated recently the diarylheptanoid and phenolic constituents of the extract of A. nikoense stem bark for their inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, and on Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA. In this paper, we describe the inhibitory effects against melanogenesis in the B16 melanoma cells and free radical scavenging activities on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical of the extracts and their diarylheptanoid and phenolic constituents of A. nikoense bark.
منابع مشابه
Antiinflammatory Constituents of Teramnus labialis
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